It may be done to diagnose or monitor chronic kidney disease. Prediction of creatinine clearance from serum creatinine. This level of creatinine is used in a formula to calculate the gfr. 170 x p cr 0999 x age 0176 x bun 0170 x albumin 0318 x 0762 for women x 1180 for blacks. K 07 for females. The american diabetes association recommends estimation of glomerular filtration rate gfr 1 by either the cockcroft gault 2 or the modification of diet in renal disease mdrd 3 equation in all patients with diabetes.
Glomerular filtration rate gfr is the volume of fluid filtered from the renal kidney glomerular capillaries into the bowmans capsule per unit time. X 085 for women 2 modification of diet in renal disease mdrd. The normal range of gfr adjusted for body surface area is 100 to 130 mlmin173m 2 in men and 90 to 120mlmin173m 2 in women below the age of 40. Body weight is a numerator in the cockcroft gault equation. Refer to the table below for population mean estimated gfr for a number of age ranges. Please fill in the following data.
Formulas used in this calculatorcreatinine clearance crcl. Cockcroft dw gault mh. The chronic kidney disease epidemiology collaboration ckd epi equation was developed as a follow up to the mdrd equation in an attempt to be as accurate in describing renal function at lower gfr less than 60 mlmin173 m 2 but more accurate at a higher gfrthe ckd epi equation was developed and validated retrospectively in 8254 patients from 10 studies. Other factors are used to calculate gfr. The implication is that these equations provide similar results. Age weight gender serum creatinine creatinine clearance value 140 ageweight kg 72 x s cr in mlmin multiply by 85 if female reference.
However it is absent from the mdrd equation. Glomerular filteration rate gfr glomerular filtration rate gfr is the best overall index of kidney function. Cockcroft gault calculator with si units plasma creatinine pcr mgdl umoll weight wt. After age 40 gfr decreases progressively with age. These include age gender weight height and race. A blood test will be done to measure the amount of creatinine in your blood.
Normal gfr varies according to age sex and body size and declines with age. How do i get ready for the test. Adult males 140 age in years x weight in kg 72 x serum cr adult females 085 x 140 age in years x weight in kg 72 x serum cr egfr per ckd epi 141 x mincrk 1 a x maxcrk 1 1209 x 0993 age x 1018if female x 1159if blackafrican american.